Betastasis

Rane, Scaravilli et al. (2015) - MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets

miRNA expression bar plot

Description

There are 42 samples in total from 5+5+3 patients: 15 benign prostatic hyperplasia (BPH), 15 prostate cancers (PCa), 9 castration-resistant prostate cancer (CRPC). There are stem cells (SC), transit amplifying cells (TA) and committed basal cells (CB) dissected from each patient. Three PrEC samples of each three cell types are used as reference.

The dataset is from GEO (ID:GSE59156) and the data from Series Matrix File available is quantile normalized using Matlab. The quantile normalized signal intensity values are then aggregated between probes for the same genes in R.